Updated : Oct 06, 2019 in Literature


Pioderma gangrenoso y fístulas enterocutáneas tras anastomosis ileoanal con reservorioGangrenous pyoderma and enterocutaneous fistulas after ileal. Introducción: la baja prevalencia de las fístulas enterocutáneas (FEC) en los pacientes con enfermedad de Crohn (EC) justifica la escasez de. Necesidad de formar unidades funcionales especializadas en el manejo médico- quirúrgico de pacientes con fístulas enterocutáneas y fracaso intestinal.

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Both EN and PN are resources that the specialist team should handle so as to indicate them, either in combination or alternatively, according to the case nature. Dig Surg ; In our experience, it has been a valuable resource in cases of high- output fistulas of gastric, duodenal and jejunal origins, when vacuum proved inconvenient, or as reinforcement of the latter if output reduction was not satisfactory.

Regarding treatment, 23 patients received infliximab with enterofutaneas mean treatment duration of 18 months, of which 7 of these enterocutxneas switched to adalimumab due to lack of response. However, it is clear that in the few studies that have evaluated or compared infliximab in perianal and enterocutaneous fistulas, the results have always been worse when compared with enterocutaneous fistulas. In recent years, enthusiasm has waned because it could be seen that, while it is effective to reduce enteric enterocutanfas, and even to accelerate some fistulas closure time, it has not been possible to demonstrate a rise in percentage of spontaneous closure or a fall in enterocutanneas rate.

The definitions of partial or complete response were based on the judgment of the treatment physician, with a retrospective measurement made using the Harvey-Bradshaw index.


Initial surgery is a valid option in patients maintaining a good general condition and is a necessity in cases where the fistula coexists with acute abdomen. The majority of these close spontaneously or with skin care, antibiotics and fluids. It should be noted that although biological drugs appeared inwe started collecting data from since the majority of patients treated with anti-TNF drugs in our series had a long disease history.

Combined approach enterochtaneas biologics and surgery for enterocutaneous fistulas in Crohn’s disease. Materials and methods Patient selection Entrrocutaneas patients with a documented history of CD who developed an ECF during their clinical progress from to were included ebterocutaneas.

Ninety-six pecent of patients received antibiotics metronidazole and ciprofloxacinwith non-response rates of Binary logistic regression was carried out by multivariate analysis of categorical risk factors. ECF was defined as postoperative or spontaneous depending on whether or not they were secondary to bowel surgery for the underlying disease.

Regarding local lesion management, 92 cases They are rare, 0. World J Surg ; 32 3: Type of fistula determines response to infliximab in patients with fistulous Crohn’s disease.

Síndrome de intestino corto y fistulas enterocutáneas by milenna luna on Prezi

Nine of them, with abdominal collections, were treated by percutaneous drainage, 2 of which were completed by directed laparotomy. The objective of this study was to evaluate the clinical characteristics of patients with CD who have ECF and the response to different treatments.

The accumulated experience throughout these years has allowed us to optimize the treatment improving in fistulas spontaneous closure and mainly obtaining a substantial mortality rate decrease. Table I shows the patients’ clinical and demographic characteristics.


They reason that dissection in a dense peritoneal reaction is prone to cause hemorrhages and bears high fistula recurrence rates [21]- [22]. There has even been a case described of an ECF that resolved with infliximab in a patient who did not have CD 8. Am J Gastroenterol ; Infliximab as a therapy for non-Crohn’s enterocutaneous fistulae. We used for these proceedings, an own digital and portable equipment designed fiistulas for treatment of enterocutaneous fistulas.

After 14 years of ffistulas, this protocol has proved it a practical resource to guide patient management.

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Global healing was possible in patients of the series Aspiration methods and octreotide were implemented as alternative or complementary options. Moderated disease activity was registered in Am J Surg ; 1: J Clin Gastroenterol 2 Controlled studies are needed in order to evaluate the efficacy of the different medical and surgical treatments available in patients with ECF.

Seventy six cases initially presented sepsis Despite employing meticulous statistical analysis, exact interpretations of these results are limited due to selection of patients and lack comparative studies. Adalimumab – an effective and promising treatment for patients with fistulizing Crohn’s disease: Most frequent primary pathologies were colorectal neoplasia, diverticulitis, abdominal trauma, appendicitis and hernia, of which 62