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J Psychiatr Res Please verify that you are not a robot. We found that discontinuation because of nonefficacy or insufficient efficacy was higher in quetiapine N2 – Background Suicide has been recognised as one of the major causes of premature death in psychosis.

Second, the mean doses of quetiapine used could be understood as somewhat low to treat first-episode individuals. Euiz all subjects More like this Similar Items.

Treatment compliance measures were collected from self-report and close observers family members and social assistants but not from antipsychotic blood levels. For this purpose, second-generation antipsychotics SGAs seem to be the mainstay of treatment due to their proven superior effectiveness compared with first-generation antipsychotics FGAs.

María Juncal-Ruiz

Privacy Policy Terms and Conditions. Patients on aripiprazole were more likely to be prescribed benzodiazepines. By the same authors Different types of childhood adversity and 5-year outcomes in a longitudinal cohort of first-episode psychosis patients Ajnakina, O. European PsychiatryVol. Differences in depressive symptom improvement between quetiapine and aripiprazole were observed, favoring the facotro group.


In those patients who continued taking the initial prescribed drug, mean antipsychotic doses at 3 years, adjusted in chlorpromazine equivalents, were aripiprazole, These factors may contribute to additional differences in terms of effectiveness.

East Dane Designer Men’s Fashion. If you are ruizz seller for this product, would you like to suggest updates through seller support? Such a high all-cause discontinuation rate represents a major issue, considering that adherence to maintenance treatment is the primary aim in FEP patients San et al. Support Center Support Center.

María Juncal-Ruiz – Semantic Scholar

Write a review Rate this item: There’s a problem loading this menu right now. Facorri second-generation antipsychotics SGAs seem to be the mainstay of treatment to improve the long-term prognosis of people with an FEP, there is scarce information about their differential effectiveness in the long term Crespo-Facorro et al.

Reviews User-contributed reviews Add a review and share your thoughts with other readers. Your list has reached the maximum number of items. I’d like to read this book on Kindle Don’t have a Kindle? Regarding the latter study, the authors also warned about a higher risk for health events related to quetiapine. You may send this item to up to five recipients. Finding libraries that hold this item The increase in discontinuations due to nonadherence observed during the last year of follow-up in this group might be explained by a natural decrease in the acceptability of treatment mediated by long-term exposure to treatment Lieberman et al.

Only those side effects rated as moderate or severe and with a possible causal relationship to medication were recorded. Would you like to tell us about a lower price? The overall dropout rate at 3 years reached Amazon Rapids Fun stories for kids on the go.


Allow this favorite library to be seen by others Keep this favorite library private. Citations rruiz based on reference standards. No significant tuiz were found in the profile of extrapyramidal symptoms. Please create a new list with a new name; move some items to a new or existing list; or delete some items.

Before starting on the assigned drug, these subjects underwent a 2- to 4-day washout period. Learn more about Amazon Prime. Conclusions Patients on quetiapine were more likely to discontinue treatment after an FEP globally and specifically at short and medium term due to nonefficacy or insufficient efficacy compared with aripiprazole and ziprasidone patients.

The present paper supplies evidence on the differences in terms of long-term effectiveness among 3 widely used SGAs aripiprazole, quetiapine, and ziprasidone.

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Are punitive parenting and stressful life events environmental risk factors for obsessive-compulsive symptoms in youth?