Updated : Oct 11, 2019 in Art

ENCEFALOPATIA DE HASHIMOTO PDF

Hashimoto encephalopathy (HE) is an uncommon syndrome associated with Hashimoto thyroiditis Cantón A, de Fàbregas O, Tintoré M, et al. Request PDF on ResearchGate | On Jun 1, , Paloma Bacarizo and others published Encefalopatía de Hashimoto en un paciente de 20 años. CLINICAL/SCIENTIFIC NOTE. Hashimoto’s encephalopathy. Encefalite de Hashimoto. Renata Telles Rudge de AquinoI; Eduardo Genaro MutarelliII.

Author: Malajas Shaktirr
Country: Oman
Language: English (Spanish)
Genre: Marketing
Published (Last): 3 May 2012
Pages: 278
PDF File Size: 10.69 Mb
ePub File Size: 18.83 Mb
ISBN: 179-9-86779-516-2
Downloads: 79265
Price: Free* [*Free Regsitration Required]
Uploader: Nazshura

In an epidemiological study made by Seipelt et al. Recent studies have shown the presence of anti-thyroid antibodies in the CSF 5 enecfalopatia alpha-enolase antibodies in the serum of patients with Hashimoto’s encephalopathy, suggesting the involvement of an autoimmune mechanism in this condition 6.

The presence rapidly progressive dementia, ataxia, myoclonus, and especially the presence of triphasic complexes in the EEG, make the diagnosis a probable one for Creutzfeldt-Jakob disease. Diagnostic criteria are encephalopathy with elevated anti-thyroid antibodies in the absence of infection, tumour or alteration in the cerebral vascular system.

Hashimoto’s encephalopathy

Hashimoto’s encephalitis HEencephalitis which responds to steroids and is associated with auto-immune thyroiditis, was described by Brain et al. Little is known about the pathogenesis.

  MAMIRE EL ULTIMO NIO PDF

Prion diseases are under compulsory notification in Brazil: Some symptoms may persist, such as tremors and loss of memory. Now, two years later, she is well and is on prednisolone 2. It is a diagnosis of exclusion in a clinical picture of encephalitis with negative investigations 2,4,7,9. Some aspects warrant particular attention: Two clinical forms have been described: Since then, about cases have been described Duration of treatment is usually between 2 and 25 years.

There followed a period of three years with difficulties at school. Views Read Edit View history. Its two sub-types can co-exist: The significance of classifying encephalopathies under the term HE will be determined in the future once the relevance of the role of antithyroid antibodies is demonstrated or dismissed by more detailed experimental and immunopathological studies.

Hashimoto’s encephalopathy.

Patients can have normal TSH and hypo or hyperthyroidism 2,4,8. Up to there were almost published case reports of this disease. Post-mortem studies of some individuals have shown lymphocytic vasculitis of venules and veins in the brain-stem and a diffuse gliosis involving gray matter more than white matter.

Prominent triphasic waves, focal slowing, epileptiform abnormalities, photoparoxysmal and photomyogenic responses may be seen. Hashimoto’s encephalopathy mimicking Creutzfeldt-Jakob disease: The majority of patients return to their normal neurological state.

  FREDERIC DARD SAN ANTONIO PDF

The recognition of this pathology and the treatment with immunosuppressant therapy determined the regression of the clinical presentation and changes in the EEG.

It is associated with Hashimoto’s thyroiditis. How to cite this article. A female patient, years-old, Caucasian, widow, born in Rio de Janeiro, developed a clinical presentation of daily sadness, discouragement, decreased appetite, insomnia, and cognitive decline.

Hashimoto’s encephalopathy.

Services on Demand Journal. J Neurol Neurosurg Psychiatry ; J Clin Endocrinol Metab ; At present, it is unclear whether antithyroid antibodies represent an immune epiphenomenon in a subset of patients with encephalopathic processes or they are really associated with pathogenic mechanisms of the disorder.

Thyroid antibodies — both anti-thyroid peroxidase antibodies anti-TPO, anti-thyroid microsomal antibodies, anti-M and anti thyroglobulin antibodies anti-Tg — in the disease re elevated but their levels do not hashijoto with the severity.

Accepted 23 September For many other patients, the condition may result in ongoing problems with a variety of manifestations, often confusing clinicians due to the diffuse nature of symptoms.