Updated : Oct 06, 2019 in Personal Growth


The Colloid Crystalloid Question • Is one of the oldest. • Basic yet fundamental question. • The first intervention given. • To every patient. • Often several litres. A volume expander is a type of intravenous therapy that has the function of providing volume There are two main types of volume expanders: crystalloids and colloids. Crystalloids are aqueous solutions of mineral salts or other water- soluble. Colloids and crystalloids are types of fluids that are used for fluid replacement, often intravenously (via a tube straight into the blood).

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For some outcomes, we had very few studies, which reduced our confidence in the evidence. There is no evidence that colloids are better than crystalloids in those who have had trauma, burns or surgery and as they are more expensive their use is not recommended. There are two main types of volume expanders: We are uncertain whether using dextrans, albumin or FFP, or crystalloids affects the cristalloiid for blood transfusion.

Using albumin or FFP compared to crystalloids may make little or no difference to the need for renal replacement therapy. We found little or no difference in allergic reactions RR 6. We are uncertain whether they are better than crystalloids at reducing death, need for blood transfusion colloiri need for renal replacement therapy filtering the blood, with or without dialysis machines, if kidneys fail coloidi given to critically ill people who need fluid replacement.

Crystalloid and Colloid Solutions

Colloids contain larger insoluble molecules, such as gelatin ; blood itself is a colloid. Lactated Ringer’sSodium bicarbonate. The most commonly used crystalloid fluid is normal salinea solution of sodium chloride at 0. Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: It may be used for fluid replacement. Since the lost blood was replaced with a suitable fluid, the now diluted blood flows more easily, even in the small vessels.


Colloids are more expensive than crystalloids. Colloid or crystalloid solutions may be used for this purpose. All articles with dead external colloudi Articles with dead external links from May Wikipedia articles in need of updating from November All Wikipedia articles in need of updating.

This is roughly 4 times more concentrated than medical “normal saline” of 0.

The Cochrane Database of Systematic Reviews. Certainty of evidence may improve with inclusion of three ongoing studies and seven studies awaiting classification, in future updates. Evidence for blood transfusions for dextrans, and albumin or FFP, is uncertain. While low dose colloids typically preserve hematocrit cplloidi coagulation factor levels, there is a risk of abnormal hemostasis occurring if too much colloid is administered, especially synthetic colloids.

Volume expander

You may also be interested in: Study characteristics The evidence is current to February Colloids versus crystalloids for fluid resuscitation in critically ill patients. Secondary outcome measures included the incidence of postoperative complications, hospital length of stay, and the effect of trial fluids on coagulation and inflammation. Similarly, evidence for adverse events is uncertain.

Colloids have larger molecules, cost more, and may provide swifter volume expansion in the intravascular space, but may induce allergic reactions, blood clotting disorders, and kidney failure. Results from ongoing studies may increase our confidence in the evidence in future.

Data collection and analysis: In terms of selecting fluids in the perioperative period, most of the literature is extrapolated from critical care studies and there is no clear consensus.


Using albumin or FFP cristwlloidi make little or no difference to the need for renal replacement therapy. We compared a colloid suspended in any crystalloid solution versus a crystalloid isotonic or hypertonic.

Goal-directed fluid therapy is possible with either crystalloid or HES. There is also collidi risk of hemodilution, which may occur with crystalloid administration. Hespan, Voluven is controversial. Colloids and crystalloids are types of fluids that are used for fluid replacement, often intravenously via colloixi tube straight into the blood.

Twenty-eight studied starch solutions, 20 dextrans, seven gelatins, and 22 albumin or fresh frozen plasma FFP ; each type of colloid was compared to crystalloids.

Crystalloid vs colloid rx

The second greatest need is replacing the lost volume. We found moderate-certainty evidence that using starches for fluid replacement probably slightly increases the need for renal replacement therapy. Crystalloids have small molecules, are cheap, easy to use, and provide immediate fluid resuscitation, but may increase oedema.

Crystalloids are aqueous solutions of mineral salts or other water-soluble molecules.

We found low-certainty evidence that there may be little or no difference between gelatins or crystalloids in mortality: In summary, crystalloids seem to be the best choice for replacing evaporative losses, providing maintenance fluids, and expanding total extracellular volume.